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WHAT IS DEPRESSION?¹ Depression is a constant feeling of sadness, loss, or anger that interferes with a person's everyday activities and relationships. Sign and Symptoms' Feeling tired/depressed mood Lost or gained weight Worthless or guilty feeling Difficulty in focusing and making decisions Sleeplessness and restlessness Suicidal ideation No interest or pleasure in any activities References: Management options' Pharmacotherapy Doctor or psychiatrist may prescribe antidepressant medications to relieve symptoms. Psychotherapy Helps to treat depression by talking about your condition and related issues with a mental health professional.